HMGCR抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
HMGCR抗体

HMGCR抗体

商家询价

产品名称： HMGCR抗体

英文名称： HMGCRAntibody

产品编号： XY13533-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 HMGCR抗体

Applications
In-house applications ELISA, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 13533-1-AP;human liver cancer tissueImmunohistochemistry of paraffin-embedded human liver cancer tissue slide using 13533-1-AP( HMGCR Antibody) at dilution of 1:50 (under 10x lens)
  • 13533-1-AP;human liver cancer tissueImmunohistochemistry of paraffin-embedded human liver cancer tissue slide using 13533-1-AP( HMGCR Antibody) at dilution of 1:50 (under 40x lens)
Positive IHC detected in Human liver cancer tissue, human heart tissue
Recommended dilution IHC : 1:20-1:200
 HMGCR抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen HMGCR fusion protein ag4444 Full name 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Calculated molecular
weight		 888aa,95 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC033692 Gene ID (NCBI) 3156
Gene symbol HMGCR Synonyms HMG CoA reductase, HMGCR
Background HMGCR抗体

HMGCR(3-hydroxy-3-methylglutaryl-coenzyme A reductase) is also named as HMG-CoA reductase and belongs to the HMG-CoA reductase family. This protein exists as a 97-kDa glycoprotein in the endoplasmic reticulum (ER) and is the rate-determining enzyme of the biosynthesis pathway(PMID:15830340).The ectopic expression of either full-length HMGCR or its novel splice variant promotes dysregulation of the MVA pathway. And the ectopic expression of cHMGCR-FL(60 kDa) and cHMGCR-D13(55 kDa) can be detected in HepG2 cells(PMID:20696928).This protein is also can exsit as a oligomer(PMID:20696928). HMGCR抗体

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